Antigen shedding into the circulation contributes to tumor immune escape
نویسندگان
چکیده
Tumors employ various mechanisms to escape elimination by the immune system. In addition to the local induction of immunosuppressive cell types such as regulatory T cells or myeloid derived suppressor cells, tumor antigen shedding into the circulation may suppress antitumor CD8(+) T-cell function via tolerogenic liver sinusoidal endothelial cells.
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عنوان ژورنال:
دوره 1 شماره
صفحات -
تاریخ انتشار 2012